ASGR1 and CLDN7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ASGR1	CLDN7
Description		asialoglycoprotein receptor 1	claudin 7
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Metal Ion Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways		Asparagine N-linked glycosylation	Tight junction interactions
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Low density lipoprotein cholesterol levels ( 32154731 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 33547301 31666285 29403010 33339817) Total cholesterol levels ( 33339817)	Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		44 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 PLS3 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR	77 interacting genes: AIG1 ANKRD46 APOD AQP2 ASGR1 BCL2L2 BET1 BMP10 C3orf52 CD53 CD72 CLN6 CMTM5 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB561D2 CYB5B CYBC1 EDDM3B EMP3 EPCAM ERG28 ERMP1 FAXDC2 FXYD6 GIMAP5 GLP1R GPR37L1 HGD IGFBP5 ITM2A JAGN1 LAT LEPROTL1 LPAR3 LSMEM2 MAL MALL MFSD5 MS4A13 NDUFB11 NIPAL4 NKG7 OLFM4 PGAP2 PLN RHOXF2 RPRM RTP2 SCAMP4 SCARF1 SEC22B SERTM1 SLC38A7 SYNE4 TJP1 TMEM100 TMEM11 TMEM128 TMEM140 TMEM147 TMEM44 TMEM60 TMEM97 TNF TRARG1 TSPAN33 UBIAD1 UNC93B1 UPK1B UPK2 VAMP3 VAMP5 VSTM1
Entrez ID		432	1366
HPRD ID		00151	07633
Ensembl ID		ENSG00000141505	ENSG00000181885
Uniprot IDs		P07306 Q6FGQ5	A0A384ME58 F5H496 O95471
PDB IDs		1DV8 5JPV 5JQ1 6YAU
Enriched GO Terms of Interacting Partners?
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