PLS3 and CXCR5

		PLS3	CXCR5
Description		plastin 3	C-X-C motif chemokine receptor 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Actin Filament Plasma Membrane Actin Filament Bundle	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Calcium Ion Binding Actin Filament Binding	G Protein-coupled Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Actin Filament Bundle Assembly Actin Filament Network Formation Bone Development	Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Leukocyte Chemotaxis Positive Regulation Of Cytokinesis B Cell Activation Lymph Node Development Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Preterm birth (maternal effect) ( 28877031)	Albumin-globulin ratio ( 29403010) Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31959851 30929738 34103634 32296059) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Celiac disease and Rheumatoid arthritis ( 26546613) Follicular lymphoma ( 25279986) Human herpesÂ virusÂ 7 U14Â antibodyÂ levels ( 33204752) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 24076602 21833088) Post-bronchodilator lung function in asthma (FVC) ( 32989782) Primary biliary cholangitis ( 28425483 21399635 26394269) Refractive error ( 32231278) Rheumatoid arthritis ( 30423114 24390342) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 32771030) Trunk fat mass ( 28552196) Vitiligo ( 22951725)
Interacting Genes		17 interacting genes: ACRV1 APP ASGR1 ATXN2 CUL4B CXCR5 FRYL LRCH2 NRSN1 OGT PTPN5 TGIF2 TRPC5 TSPAN32 WFDC2 ZBTB33 ZNF195	7 interacting genes: ARCN1 CBL CXCL13 DPAGT1 MRE11 PLS3 TLK1
Entrez ID		5358	643
HPRD ID		02133	03367
Ensembl ID		ENSG00000102024	ENSG00000160683
Uniprot IDs		B4DPW9 P13797	A0N0R2 A8K647 P32302 Q2YD84
PDB IDs		1AOA 1WJO
Enriched GO Terms of Interacting Partners?
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