PAK1 and SORBS2

  • Number of citations of the paper that reports this interaction (PubMedID 15784622)
  • 13
  • Data Source:
  • HPRD (in vitro, in vivo)

PAK1

SORBS2

Description p21 (RAC1) activated kinase 1 sorbin and SH3 domain containing 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiac Troponin-T levels ( 31014085)
  • Coronary artery disease ( 33020668)
  • Cytokine and corticosteroid-stimulated IL-6 production ( 25896417)
  • Cytokine-stimulated IL-6 production ( 25896417)
  • Height ( 31562340)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Short-term memory (digit-span task) ( 30741946)
  • Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
  • Uterine fibroid size (maximum volume) ( 30196971)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes 85 interacting genes: ABI3 ACTA1 ACVR1 AKT1 APP ARHGEF2 ARHGEF6 ARHGEF7 ARPC1B BAD BAIAP2 BMPR1B BMX BRSK1 CASP1 CDC42 CDK11B CDK5 CDK5R1 CHORDC1 COL1A1 CPLANE1 CSNK2A1 CSNK2A2 DSCAM DYNLL1 DYNLL2 DYRK1B EGFR ELF3 ERBB2 ESR1 FLNA FOXL2 FOXO1 FRS2 GIT2 GRB2 H3C1 H4C1 HACE1 HGS HSP90AA1 LIMK1 MAP2K1 MAP3K1 MAPK1 MBP MYLK MYNN MYO6 NCK1 NCK2 NF2 OXSR1 PAK1IP1 PDPK1 PLCG1 PPM1A PPM1F PPP1CA PPP2CA PRKCD PXN RAC1 RAF1 RHOJ RHOU SHC1 SMAD1 SMAD2 SMAD4 SMURF1 SORBS2 SYN1 TGFBR1 TGFBR2 TGM2 YWHAG YWHAZ ZBTB18 ZC3H7A ZNF418 ZNF823 ZNF83 47 interacting genes: ABI1 ABL1 ABL2 ACTN1 ACTN4 ADAM15 AFDN AKT1 AKT2 ATPAF2 CBL CBLB DLGAP1 DLGAP2 DLGAP4 DYNC1H1 EFS EGFR EIF3H FAT1 FLOT1 GOLGA2 MDM2 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SH3RF1 SHANK3 SOCS7 SYNJ1 TEPSIN TRAF4 VCL VPS37C WAS WASF1 WASL YWHAE YWHAZ
Entrez ID 5058 8470
HPRD ID 03995 12473
Ensembl ID ENSG00000149269 ENSG00000154556
Uniprot IDs A0A024R5P0 Q13153 B7Z3D7 B7Z997 O94875
PDB IDs 1F3M 1YHV 1YHW 1ZSG 2HY8 2QME 3DVP 3FXZ 3FY0 3Q4Z 3Q52 3Q53 4DAW 4EQC 4O0R 4O0T 4P90 4ZJI 4ZJJ 4ZLO 4ZY4 4ZY5 4ZY6 5DEW 5DEY 5DFP 5IME 5KBQ 5KBR 6B16 5VEI
Enriched GO Terms of Interacting Partners?
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