SORBS2 and WAS

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 484
  • Data Source:
  • BioGRID (two hybrid)

SORBS2

WAS

Description sorbin and SH3 domain containing 2 WASP actin nucleation promoting factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiac Troponin-T levels ( 31014085)
  • Coronary artery disease ( 33020668)
  • Cytokine and corticosteroid-stimulated IL-6 production ( 25896417)
  • Cytokine-stimulated IL-6 production ( 25896417)
  • Height ( 31562340)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Short-term memory (digit-span task) ( 30741946)
  • Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
  • Uterine fibroid size (maximum volume) ( 30196971)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Platelet distribution width ( 32888494)
Interacting Genes 47 interacting genes: ABI1 ABL1 ABL2 ACTN1 ACTN4 ADAM15 AFDN AKT1 AKT2 ATPAF2 CBL CBLB DLGAP1 DLGAP2 DLGAP4 DYNC1H1 EFS EGFR EIF3H FAT1 FLOT1 GOLGA2 MDM2 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SH3RF1 SHANK3 SOCS7 SYNJ1 TEPSIN TRAF4 VCL VPS37C WAS WASF1 WASL YWHAE YWHAZ 57 interacting genes: ABI3 ACTC1 APBB1 APPBP2 ARHGAP1 ARHGEF7 ARPC1B ARPC2 ARPC3 BAIAP2L1 BTK C5AR1 CDC42 CIB1 CREBBP CRKL CSNK2A1 CSNK2A2 DLG1 DVL2 ENAH EVL FCHSD2 FGR FYB1 FYN GRB2 HCK HCLS1 ITK ITSN2 LCK LCP2 NCK1 NCK2 NCKIPSD PIK3R1 PLCG1 PRPF40A PSTPIP1 PTPN12 RAC1 RANBP2 RGS14 RHOJ SNX9 SORBS2 SRC TCERG1 TEC TNK2 TRIP10 UBASH3A VASP WBP4 WIPF1 WIPF2
Entrez ID 8470 7454
HPRD ID 12473 02314
Ensembl ID ENSG00000154556 ENSG00000015285
Uniprot IDs B7Z3D7 B7Z997 O94875 A0A024QYX8 P42768
PDB IDs 5VEI 1CEE 1EJ5 1T84 2A3Z 2K42 2OT0
Enriched GO Terms of Interacting Partners?
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