SORBS2 and NCK2

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 484
  • Data Source:
  • BioGRID (two hybrid)

SORBS2

NCK2

Description sorbin and SH3 domain containing 2 NCK adaptor protein 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiac Troponin-T levels ( 31014085)
  • Coronary artery disease ( 33020668)
  • Cytokine and corticosteroid-stimulated IL-6 production ( 25896417)
  • Cytokine-stimulated IL-6 production ( 25896417)
  • Height ( 31562340)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Short-term memory (digit-span task) ( 30741946)
  • Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
  • Uterine fibroid size (maximum volume) ( 30196971)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Addiction ( 23533358)
  • Alzheimer's disease or family history of Alzheimer's disease ( 33589840)
  • Anti-chlamydia trachomatis IgG seropositivity ( 33204752)
  • Mean platelet volume ( 32888494)
  • Platelet distribution width ( 32888494 27863252)
  • Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes 47 interacting genes: ABI1 ABL1 ABL2 ACTN1 ACTN4 ADAM15 AFDN AKT1 AKT2 ATPAF2 CBL CBLB DLGAP1 DLGAP2 DLGAP4 DYNC1H1 EFS EGFR EIF3H FAT1 FLOT1 GOLGA2 MDM2 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SH3RF1 SHANK3 SOCS7 SYNJ1 TEPSIN TRAF4 VCL VPS37C WAS WASF1 WASL YWHAE YWHAZ 171 interacting genes: ABI1 ABI2 ABI3 ANKRD55 ANKS1B ARHGAP32 ATN1 AXIN1 AXL BCAR1 BCL11A BTG1 C4orf17 CBARP CBLB CCDC120 CCDC33 CD3E CHN1 CHN2 CIB1 CIPC CLEC17A CPSF6 CPSF7 CUEDC1 DDR1 DEFB124 DISC1 DLGAP4 DNM1 DOCK1 DOK1 DRAP1 DTX3 DVL1 EEF1G EFHC2 EFNB1 EFNB2 EFS EGFR EIF3H ERBB2 ERBB3 ERBB4 FAM124A FAM47A FAM53C FAM83A FASLG FBXL19 FCRL2 FGFR1 FOSB FXR2 FYB1 GAB1 GAREM1 GGN HNRNPK HOMEZ HOXA1 HOXC4 HOXD8 HSF2BP ILK INCA1 INTS2 IRS1 KCTD17 KHDRBS1 KIAA0408 KIAA1217 KIT KLHL24 KLHL35 KPRP LCP2 LIMS1 LNX1 LRRIQ3 LZTS2 MAGEA6 MASP1 MBD6 MEOX2 MET MIA3 MNT MYPOP NCKIPSD NELFA NET1 NFKBID NHSL2 NPAS2 NPHS1 NR5A1 NTRK2 NUTM2F ONECUT3 PAK1 PAK2 PBX4 PDGFRB PHETA1 PIK3AP1 PKD1 PKN2 PRDM6 PRR16 PRR20A PRR20B PRR20C PRR20D PRR20E PSMD10 PTK2 RASSF7 RBBP8NL RBM26 REEP4 REL SCML2 SCX SF1 SF3A2 SF3B4 SHD SKAP2 SMARCB1 SNW1 SOCS7 SORBS2 SOS1 SPATA2L SPATC1L SPRY2 SRMS SRPK1 SRPK2 SSH3 SYNGAP1 SYNPO TCF4 TCP10L TMEM121 TNR TRIM27 TRIM41 TRIP6 TXK UBC USP32 VARS2 VPS37B WAS WASF1 WASL WBP11 WIPF1 WIPF2 ZBTB12 ZBTB42 ZBTB7B ZC2HC1A ZC2HC1B ZNF341 ZNF526 ZNF688
Entrez ID 8470 8440
HPRD ID 12473 05378
Ensembl ID ENSG00000154556 ENSG00000071051
Uniprot IDs B7Z3D7 B7Z997 O94875 A0A0S2Z4M6 E7ERP6 O43639
PDB IDs 5VEI 1U5S 1WX6 1Z3K 2B86 2CIA 2FRW 2FRY 2JXB 4E6R
Enriched GO Terms of Interacting Partners?
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