SORBS2 and PTPN12

  • Number of citations of the paper that reports this interaction (PubMedID 18559503)
  • 22
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology)

SORBS2

PTPN12

Description sorbin and SH3 domain containing 2 protein tyrosine phosphatase non-receptor type 12
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiac Troponin-T levels ( 31014085)
  • Coronary artery disease ( 33020668)
  • Cytokine and corticosteroid-stimulated IL-6 production ( 25896417)
  • Cytokine-stimulated IL-6 production ( 25896417)
  • Height ( 31562340)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Short-term memory (digit-span task) ( 30741946)
  • Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
  • Uterine fibroid size (maximum volume) ( 30196971)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Body shape index ( 34021172)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Estimated glomerular filtration rate ( 31015462)
  • Lymphocyte counts ( 32888494)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 47 interacting genes: ABI1 ABL1 ABL2 ACTN1 ACTN4 ADAM15 AFDN AKT1 AKT2 ATPAF2 CBL CBLB DLGAP1 DLGAP2 DLGAP4 DYNC1H1 EFS EGFR EIF3H FAT1 FLOT1 GOLGA2 MDM2 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SH3RF1 SHANK3 SOCS7 SYNJ1 TEPSIN TRAF4 VCL VPS37C WAS WASF1 WASL YWHAE YWHAZ 59 interacting genes: AATK ABL1 ANP32B APP BAG6 BCAR1 CCDC180 CGA CSH1 CSH2 CSK EFS EGFR EIF4H ERBB3 ERBB4 FANCC FGFR2 FGFR4 FLT3 FRAT2 GRB2 IFT20 IGF1R INSR JAK2 KDR LMTK2 LPXN MYCBP2 NEDD9 PPP3R2 PRKACA PRKCA PSG9 PSTPIP1 PSTPIP2 PTK2 PTK2B PTK7 PXN RBM19 ROR2 RUNX1 SFRP4 SHC1 SMAD1 SMAD5 SORBS2 STX16 STX17 TENM1 TEX10 TGFB1I1 THAP2 UTRN WAS ZFP2 ZNF510
Entrez ID 8470 5782
HPRD ID 12473 02513
Ensembl ID ENSG00000154556 ENSG00000127947
Uniprot IDs B7Z3D7 B7Z997 O94875 B4E105 Q05209
PDB IDs 5VEI 5HDE 5J8R 5O2P
Enriched GO Terms of Interacting Partners?
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