ASGR2 and GLUD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ASGR2	GLUD1
Description		asialoglycoprotein receptor 2	glutamate dehydrogenase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm	Cytoplasm Mitochondrion Mitochondrial Matrix Endoplasmic Reticulum
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Glutamate Dehydrogenase (NADP+) Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding
	Biological Process	Endocytosis Cell Surface Receptor Signaling Pathway Glycoprotein Metabolic Process Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Tricarboxylic Acid Metabolic Process
Pathways		Asparagine N-linked glycosylation	Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism
Drugs		Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa	Glutamic acid NADH Hexachlorophene Guanosine-5'-Triphosphate Aluminum chloride
Diseases
GWAS		Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Total cholesterol levels ( 30275531)	Renal underexcretion gout ( 32238385)
Interacting Genes		51 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A CTNNB1 EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 HNF1B IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1	13 interacting genes: ASGR2 CRP CTNNB1 DYNLL1 GOT2 HPX HSD17B10 LSM1 NR4A1 OGT ORM1 STAT5A VTN
Entrez ID		433	2746
HPRD ID		00152	11748
Ensembl ID		ENSG00000161944	ENSG00000148672
Uniprot IDs		P07307 Q7Z4G9	E9KL48 P00367
PDB IDs			1L1F 1NR1 6DQG
Enriched GO Terms of Interacting Partners?
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