ASGR2 and CLEC17A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ASGR2	CLEC17A
Description		asialoglycoprotein receptor 2	C-type lectin domain containing 17A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm	Cell Surface Integral Component Of Membrane
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding	Protein Binding Mannose Binding Identical Protein Binding Fucose Binding Metal Ion Binding
	Biological Process	Endocytosis Cell Surface Receptor Signaling Pathway Glycoprotein Metabolic Process Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis
Pathways		Asparagine N-linked glycosylation
Drugs		Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases
GWAS		Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Total cholesterol levels ( 30275531)	Iris color (L* coordinate) ( 30895295) Low density lipoprotein cholesterol levels ( 33339817) Response to antidepressants (symptom improvement) ( 29160301) Total cholesterol levels ( 33339817)
Interacting Genes		51 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A CTNNB1 EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 HNF1B IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1	21 interacting genes: ASGR2 ATP6V0C CLDN8 CTXN3 CXCL9 FAM3C GPR152 IGFBP5 NCK2 NINJ2 OLFM4 PELI1 PELI2 RPRM SEC23A SMIM3 TM4SF4 TMEM140 TMEM201 TMEM218 UPK2
Entrez ID		433	388512
HPRD ID		00152	16993
Ensembl ID		ENSG00000161944	ENSG00000187912
Uniprot IDs		P07307 Q7Z4G9	Q6ZS10
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?