ASGR2 and MCEMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ASGR2	MCEMP1
Description		asialoglycoprotein receptor 2	mast cell expressed membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Tertiary Granule Membrane
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding	Protein Binding Identical Protein Binding
	Biological Process	Endocytosis Cell Surface Receptor Signaling Pathway Glycoprotein Metabolic Process Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis
Pathways		Asparagine N-linked glycosylation	Neutrophil degranulation
Drugs		Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases
GWAS		Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Total cholesterol levels ( 30275531)
Interacting Genes		51 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A CTNNB1 EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 HNF1B IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1	10 interacting genes: ARL6IP1 ASGR1 ASGR2 ATP6V0C CMTM5 CNIH1 DGAT2L6 MALL PRAF2 ZDHHC15
Entrez ID		433	199675
HPRD ID		00152	14119
Ensembl ID		ENSG00000161944	ENSG00000183019
Uniprot IDs		P07307 Q7Z4G9	A0A384NYE9 Q8IX19
PDB IDs
Enriched GO Terms of Interacting Partners?
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