ASGR2 and MROH5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ASGR2	MROH5
Description		asialoglycoprotein receptor 2	maestro heat like repeat family member 5 (gene/pseudogene)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Endocytosis Cell Surface Receptor Signaling Pathway Glycoprotein Metabolic Process Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis
Pathways		Asparagine N-linked glycosylation
Drugs		Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases
GWAS		Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Total cholesterol levels ( 30275531)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder ( 30804558) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Response to antidepressants (symptom improvement) ( 29160301)
Interacting Genes		51 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A CTNNB1 EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 HNF1B IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1	2 interacting genes: ASGR2 SPATC1
Entrez ID		433	389690
HPRD ID		00152	13480
Ensembl ID		ENSG00000161944	ENSG00000226807
Uniprot IDs		P07307 Q7Z4G9	Q6ZMW9 Q6ZUA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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