GLUD1 and HPX

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GLUD1	HPX
Description		glutamate dehydrogenase 1	hemopexin
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Endoplasmic Reticulum	Extracellular Region Extracellular Space Collagen-containing Extracellular Matrix Extracellular Exosome Endocytic Vesicle Lumen Blood Microparticle
	Molecular Function	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Glutamate Dehydrogenase (NADP+) Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding	Protein Binding Heme Transmembrane Transporter Activity Metal Ion Binding
	Biological Process	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Tricarboxylic Acid Metabolic Process	Positive Regulation Of Immunoglobulin Production Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Cellular Iron Ion Homeostasis Heme Transport Hemoglobin Metabolic Process Heme Metabolic Process Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Interferon-gamma-mediated Signaling Pathway
Pathways		Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism	Scavenging of heme from plasma
Drugs		Glutamic acid NADH Hexachlorophene Guanosine-5'-Triphosphate Aluminum chloride	Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Renal underexcretion gout ( 32238385)	Blood protein levels ( 29875488) Malaria ( 31844061)
Interacting Genes		13 interacting genes: ASGR2 CRP CTNNB1 DYNLL1 GOT2 HPX HSD17B10 LSM1 NR4A1 OGT ORM1 STAT5A VTN	4 interacting genes: GLUD1 HSP90AA1 LINC02582 TP63
Entrez ID		2746	3263
HPRD ID		11748	00793
Ensembl ID		ENSG00000148672	ENSG00000110169
Uniprot IDs		E9KL48 P00367	P02790 Q9BS19
PDB IDs		1L1F 1NR1 6DQG
Enriched GO Terms of Interacting Partners?
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