KRT14 and KRT5

Number of citations of the paper that reports this interaction (PubMedID 8636216)
122

Data Source:
HPRD (in vitro)

		KRT14	KRT5
Description		keratin 14	keratin 5
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Keratin Filament Basal Part Of Cell Extracellular Exosome Cell Periphery	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Keratin Filament Binding	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Aging Epidermis Development Response To Zinc Ion Response To Ionizing Radiation Epithelial Cell Differentiation Hair Cycle Intermediate Filament Bundle Assembly	Cytoskeleton Organization Epidermis Development
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope	Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate	Zinc Zinc acetate
Diseases
GWAS			Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Interacting Genes		32 interacting genes: ABI2 ABI3 AMOT APC BFSP2 CTTNBP2 DST ENKD1 GAS8 HGS HSPA5 KIFC3 KRT1 KRT3 KRT5 KRT6C KRT72 KRT78 KRT79 KRT80 KRT81 KRT86 OIP5 PKP1 PRPH PUS10 SDCBP SMARCE1 TCHP TRADD UBASH3A USHBP1	35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A
Entrez ID		3861	3852
HPRD ID		01017	01010
Ensembl ID		ENSG00000186847	ENSG00000186081
Uniprot IDs		P02533	P13647
PDB IDs		3TNU 6JFV	3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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