KRT5 and KRT6A

		KRT5	KRT6A
Description		keratin 5	keratin 6A
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Cytoskeleton Organization Epidermis Development	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate	Zinc Zinc acetate
Diseases
GWAS		Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)	Cutaneous squamous cell carcinoma ( 32041948)
Interacting Genes		35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A	50 interacting genes: BEX2 CCDC85B CCR1 DSP GEM GNL1 GOLGA2 HGS KDM1A KIFC3 KRT1 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT34 KRT35 KRT36 KRT38 KRT4 KRT40 KRT5 KRT6B KRT7 LMNA MTUS2 NCALD NUP62 PRPH RND1 SGTA SMARCB1 TARBP2 TCHP TFIP11 TMBIM6 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3
Entrez ID		3852	3853
HPRD ID		01010	01011
Ensembl ID		ENSG00000186081	ENSG00000205420
Uniprot IDs		P13647	A0A0S2Z428 P02538
PDB IDs		3TNU 6JFV	5KI0
Enriched GO Terms of Interacting Partners?
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