KRT5 and KRT4

		KRT5	KRT4
Description		keratin 5	keratin 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Nucleus Cytosol Intermediate Filament Cell Surface Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Protein Binding
	Biological Process	Cytoskeleton Organization Epidermis Development	Cytoskeleton Organization Epithelial Cell Differentiation Negative Regulation Of Epithelial Cell Proliferation
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases
GWAS		Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Interacting Genes		35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A	24 interacting genes: C14orf119 CCDC57 CEP57 KRT13 KRT15 KRT16 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT35 KRT36 KRT37 KRT38 KRT40 KRT5 KRT6A PPP1R13B SUOX TRIM54 TUBGCP4
Entrez ID		3852	3851
HPRD ID		01010	00478
Ensembl ID		ENSG00000186081	ENSG00000170477
Uniprot IDs		P13647	P19013
PDB IDs		3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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