KRT5 and SORD

		KRT5	SORD
Description		keratin 5	sorbitol dehydrogenase
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Extracellular Space Cytosol Membrane Motile Cilium Mitochondrial Membrane Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	(R,R)-butanediol Dehydrogenase Activity L-iditol 2-dehydrogenase Activity Zinc Ion Binding Carbohydrate Binding Identical Protein Binding D-xylulose Reductase Activity Ribitol 2-dehydrogenase Activity NAD Binding
	Biological Process	Cytoskeleton Organization Epidermis Development	Glucose Metabolic Process Sorbitol Catabolic Process Response To Osmotic Stress Response To Xenobiotic Stimulus Response To Hormone Flagellated Sperm Motility Response To Nutrient Levels Fructose Biosynthetic Process Response To Cadmium Ion Response To Copper Ion L-xylitol Catabolic Process L-xylitol Metabolic Process
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope	Fructose biosynthesis Formation of xylulose-5-phosphate
Drugs		Zinc Zinc acetate	NADH Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine
Diseases
GWAS		Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)	Alzheimer's disease in APOE e4+ carriers ( 25778476)
Interacting Genes		35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A	3 interacting genes: KRT5 RELA SHBG
Entrez ID		3852	6652
HPRD ID		01010	01679
Ensembl ID		ENSG00000186081	ENSG00000140263
Uniprot IDs		P13647	Q00796
PDB IDs		3TNU 6JFV	1PL6 1PL7 1PL8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?