KRT5 and NADSYN1

		KRT5	NADSYN1
Description		keratin 5	NAD synthetase 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Cytoplasm Cytosol
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	NAD+ Synthase (glutamine-hydrolyzing) Activity Glutaminase Activity Protein Binding ATP Binding
	Biological Process	Cytoskeleton Organization Epidermis Development	NAD Biosynthetic Process 'de Novo' NAD Biosynthetic Process
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope	Nicotinate metabolism
Drugs		Zinc Zinc acetate	Glutamic acid
Diseases
GWAS		Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)	Systemic lupus erythematosus ( 26502338) Vitamin D insufficiency ( 20541252) Vitamin D levels ( 29343764 20418485) Vitamin D levels (dietary vitamin D intake interaction) ( 29343764)
Interacting Genes		35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A	15 interacting genes: ANKS1A COL8A1 CREB5 CUTC FRS3 GPANK1 HGS HOXC8 KRT5 MYO15B NOXA1 NTAQ1 PKD1 TFG UPF1
Entrez ID		3852	55191
HPRD ID		01010	16309
Ensembl ID		ENSG00000186081	ENSG00000172890
Uniprot IDs		P13647	Q6IA69
PDB IDs		3TNU 6JFV	6OFB
Enriched GO Terms of Interacting Partners?
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