KRT6A and TCHP

Number of citations of the paper that reports this interaction (PubMedID 15731017)
1

Data Source:
HPRD (two hybrid)

		KRT6A	TCHP
Description		keratin 6A	trichoplein keratin filament binding
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Entry Of Bacterium Into Host Cell	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways		Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases
GWAS		Cutaneous squamous cell carcinoma ( 32041948)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Myocardial infarction ( 30226566) Platelet count ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		50 interacting genes: BEX2 CCDC85B CCR1 DSP GEM GNL1 GOLGA2 HGS KDM1A KIFC3 KRT1 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT34 KRT35 KRT36 KRT38 KRT4 KRT40 KRT5 KRT6B KRT7 LMNA MTUS2 NCALD NUP62 PRPH RND1 SGTA SMARCB1 TARBP2 TCHP TFIP11 TMBIM6 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3	53 interacting genes: ATPAF2 BCAS2 C21orf91 CBY2 CCDC125 CCDC13 CCDC172 CCDC85B CDR2 CDR2L DMAP1 DYDC1 EIF4ENIF1 HOOK2 ID2 IFFO1 IKZF3 KCTD17 KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT32 KRT34 KRT35 KRT40 KRT5 KRT6A KRT75 KRT8 MIIP MIPOL1 MKRN3 MTUS2 NAB2 NDOR1 NME7 NUP54 PRDM16 PSMB5 RABGEF1 RUSC1 TEX11 TRIM27 TRIM54 TSPAN15 USHBP1 VIM WWOX ZIM2
Entrez ID		3853	84260
HPRD ID		01011	14403
Ensembl ID		ENSG00000205420	ENSG00000139437
Uniprot IDs		A0A0S2Z428 P02538	A0A024RBM9 Q9BT92
PDB IDs		5KI0
Enriched GO Terms of Interacting Partners?
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