GPD1 and KRT5

		GPD1	KRT5
Description		glycerol-3-phosphate dehydrogenase 1	keratin 5
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GO Annotations	Cellular Component	Cytosol Glycerol-3-phosphate Dehydrogenase Complex Extracellular Exosome	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Glycerol-3-phosphate Dehydrogenase [NAD+] Activity Glycerol-3-phosphate Dehydrogenase (quinone) Activity Protein Binding Protein Homodimerization Activity NAD Binding	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Glycerol-3-phosphate Metabolic Process Gluconeogenesis NADH Oxidation Glycerophosphate Shuttle Positive Regulation Of Glycolytic Process Glycerol-3-phosphate Catabolic Process Glycerolipid Metabolic Process Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor	Cytoskeleton Organization Epidermis Development
Pathways		Synthesis of PA	Type I hemidesmosome assembly Keratinization Formation of the cornified envelope
Drugs		NADH Metformin	Zinc Zinc acetate
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Hip circumference adjusted for BMI ( 34021172)	Basal cell carcinoma ( 31174203 33549134 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)
Interacting Genes		8 interacting genes: FAM25A FAM25C FAM25G GK KRT5 MDH1 POMP PTN	35 interacting genes: ALOX12 ALOX12B APC DCTN1 DSP DST EVPL GPD1 INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT4 KRT40 KRT6A KRT6B KRT7 NADSYN1 PKP2 SAP18 SORD TARBP2 TCHP UBE3A
Entrez ID		2819	3852
HPRD ID		00714	01010
Ensembl ID		ENSG00000167588	ENSG00000186081
Uniprot IDs		A0A024R138 P21695	P13647
PDB IDs		1WPQ 1X0V 1X0X 6E8Y 6E8Z 6E90 6PYP	3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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