BRMS1 and DIRAS3

Number of citations of the paper that reports this interaction (PubMedID 25640309)
8

Data Source:
BioGRID (two hybrid)

		BRMS1	DIRAS3
Description		BRMS1 transcriptional repressor and anoikis regulator	DIRAS family GTPase 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Plasma Membrane
	Molecular Function	Protein Binding Histone Deacetylase Binding NF-kappaB Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression By Genetic Imprinting Small GTPase Mediated Signal Transduction
Pathways		HDACs deacetylate histones Potential therapeutics for SARS
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)
Interacting Genes		49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	14 interacting genes: ACADM APC BAG4 BRMS1 CHEK2 FGFR4 HTR2A KRAS MEOX2 PALB2 PPM1D PTPN1 TGFB1 WT1
Entrez ID		25855	9077
HPRD ID		05879	05547
Ensembl ID		ENSG00000174744	ENSG00000162595
Uniprot IDs		G5E9I4 Q9HCU9	O95661
PDB IDs		2XUS 4AUV	6NAZ
Enriched GO Terms of Interacting Partners?
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