BRMS1 and DNAJB6

Number of citations of the paper that reports this interaction (PubMedID 16919237)
34

Data Source:
HPRD (in vivo, two hybrid)

		BRMS1	DNAJB6
Description		BRMS1 transcriptional repressor and anoikis regulator	DnaJ heat shock protein family (Hsp40) member B6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Histone Deacetylase Binding NF-kappaB Binding	ATPase Activator Activity DNA Binding Protein Binding Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Protein Folding Actin Cytoskeleton Organization Extracellular Matrix Organization Regulation Of Protein Localization Protein Localization To Nucleus Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Chaperone-mediated Protein Folding Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways		HDACs deacetylate histones Potential therapeutics for SARS	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)
Interacting Genes		49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF EPHB4 KRT18 MAP3K1 MLF1 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8
Entrez ID		25855	10049
HPRD ID		05879	07107
Ensembl ID		ENSG00000174744	ENSG00000105993
Uniprot IDs		G5E9I4 Q9HCU9	A0A0J9YX62 O75190
PDB IDs		2XUS 4AUV	6U3R 6U3S 7JSQ
Enriched GO Terms of Interacting Partners?
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