BRMS1 and SPOP

Number of citations of the paper that reports this interaction (PubMedID 22085717)
21

Data Source:
BioGRID (pull down)

		BRMS1	SPOP
Description		BRMS1 transcriptional repressor and anoikis regulator	speckle type BTB/POZ protein
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Protein Polyubiquitination Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		HDACs deacetylate histones Potential therapeutics for SARS	Hedgehog 'on' state
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Prostate cancer ( 23535732)
Interacting Genes		49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	68 interacting genes: AEN AMOTL2 AR ARIH1 BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DAXX DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 ILF3 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8
Entrez ID		25855	8405
HPRD ID		05879	16004
Ensembl ID		ENSG00000174744	ENSG00000121067
Uniprot IDs		G5E9I4 Q9HCU9	O43791
PDB IDs		2XUS 4AUV	2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A 7D3D
Enriched GO Terms of Interacting Partners?
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