DIRAS3 and ACADM

		DIRAS3	ACADM
Description		DIRAS family GTPase 3	acyl-CoA dehydrogenase medium chain
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GO Annotations	Cellular Component	Plasma Membrane	Nucleus Mitochondrion Mitochondrial Matrix Axon Mitochondrial Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Acyl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression By Genetic Imprinting Small GTPase Mediated Signal Transduction	Liver Development Glycogen Biosynthetic Process Regulation Of Gluconeogenesis Fatty Acid Beta-oxidation Response To Cold Post-embryonic Development Carnitine Metabolic Process, CoA-linked Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Response To Starvation Carnitine Biosynthetic Process Medium-chain Fatty Acid Metabolic Process Medium-chain Fatty Acid Catabolic Process Cardiac Muscle Cell Differentiation
Pathways			PPARA activates gene expression mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Drugs			Octanoyl-Coenzyme A Flavin adenine dinucleotide 3-thiaoctanoyl-CoA
Diseases
GWAS			Acylcarnitine levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Daytime sleep phenotypes ( 27126917) Glycine levels ( 31070104 30837465) Metabolic traits ( 21886157) Metabolite levels ( 20037589) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748 23093944) Serum metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		14 interacting genes: ACADM APC BAG4 BRMS1 CHEK2 FGFR4 HTR2A KRAS MEOX2 PALB2 PPM1D PTPN1 TGFB1 WT1	8 interacting genes: ABCD3 AGTR1 CALM1 CDC42 DBT DIRAS3 MSH4 SUMO4
Entrez ID		9077	34
HPRD ID		05547	08447
Ensembl ID		ENSG00000162595	ENSG00000117054
Uniprot IDs		O95661	A0A0S2Z366 B4DJE7 B7Z9I1 F6YB23 P11310 Q5HYG7 Q5T4U5
PDB IDs		6NAZ	1EGC 1EGD 1EGE 1T9G 2A1T 4P13
Enriched GO Terms of Interacting Partners?
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