SPOP and BRD2

Number of citations of the paper that reports this interaction (PubMedID 31776466)
7

Data Source:
BioGRID (two hybrid)

		SPOP	BRD2
Description		speckle type BTB/POZ protein	bromodomain containing 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Cul3-RING Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Chromatin Binding Protein Serine/threonine Kinase Activity Protein Binding Lysine-acetylated Histone Binding
	Biological Process	Protein Polyubiquitination Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Neural Tube Closure Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Spermatogenesis
Pathways		Hedgehog 'on' state	RUNX3 regulates p14-ARF
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 28008999) Feeling nervous ( 29500382) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28008999) Ulcerative colitis ( 28008999)
Interacting Genes		68 interacting genes: AEN AMOTL2 AR ARIH1 BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DAXX DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 ILF3 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8	18 interacting genes: CDC42EP4 CLCN2 DDR1 E2F1 E2F2 ECEL1 H2BC21 H2BU1 H4-16 HLA-DQA1 HOXC6 PHF1 PRNP PSMB9 RAC2 SPOP TBP TOP1
Entrez ID		8405	6046
HPRD ID		16004	03326
Ensembl ID		ENSG00000121067	ENSG00000204256
Uniprot IDs		O43791	A0A024RCR5 A0A1U9X7A8 P25440 X5CF57
PDB IDs		2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A 7D3D	1X0J 2DVQ 2DVR 2DVS 2DVV 2E3K 2G4A 2YDW 2YEK 3AQA 3ONI 4A9E 4A9F 4A9H 4A9I 4A9J 4A9M 4A9N 4A9O 4AKN 4ALG 4ALH 4J1P 4MR5 4MR6 4QEU 4QEV 4QEW 4UYF 4UYG 4UYH 5BT5 5DFB 5DFC 5DFD 5DW1 5EK9 5HEL 5HEM 5HEN 5HFQ 5IBN 5IG6 5N2L 5O38 5O39 5O3A 5O3B 5O3C 5O3D 5O3E 5O3F 5O3G 5O3H 5O3I 5U5S 5U6V 5UEW 5XHE 5XHK 6CUI 6DB0 6DBC 6DDI 6DDJ 6E6J 6FFE 6FFF 6FFG 6I80 6I81 6JKE 6K04 6K05 6MO7 6MO8 6MO9 6MOA 6ONY 6SWO 6SWP 6TQ1 6TQ2 6U61 6U71 6U8H 6ULQ 6ULT 6VIY 6YTM 6Z7F 6Z8P 6ZB0 6ZB1 6ZB2 7JX7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?