SIGMAR1 and RUSC2

		SIGMAR1	RUSC2
Description		sigma non-opioid intracellular receptor 1	RUN and SH3 domain containing 2
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GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane	Cytosol Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	G Protein-coupled Opioid Receptor Activity Protein Binding	Protein Binding Small GTPase Binding
	Biological Process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide G Protein-coupled Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization	Biological_process
Pathways		Potential therapeutics for SARS
Drugs		Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS			Psoriasis ( 25903422)
Interacting Genes		14 interacting genes: ANK2 DCAF12 DNAJB5 GHSR GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 VCP	11 interacting genes: DLST EGFR FXR1 GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SIGMAR1 SRPRA
Entrez ID		10280	9853
HPRD ID		03580	18009
Ensembl ID		ENSG00000147955	ENSG00000198853
Uniprot IDs		A2A3U5 B4DR71 Q99720	Q8N2Y8
PDB IDs		5HK1 5HK2 6DJZ 6DK0 6DK1	6IF2
Enriched GO Terms of Interacting Partners?
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