RUSC2 and GIT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		RUSC2	GIT2
Description		RUN and SH3 domain containing 2	GIT ArfGAP 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Extracellular Exosome	Nucleoplasm Focal Adhesion
	Molecular Function	Protein Binding Small GTPase Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Biological_process	Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity
Pathways			CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle
Drugs
Diseases
GWAS		Psoriasis ( 25903422)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		11 interacting genes: DLST EGFR FXR1 GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SIGMAR1 SRPRA	48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		9853	9815
HPRD ID		18009	09779
Ensembl ID		ENSG00000198853	ENSG00000139436
Uniprot IDs		Q8N2Y8	F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58
PDB IDs		6IF2
Enriched GO Terms of Interacting Partners?
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