SIGMAR1 and PDZD11

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SIGMAR1	PDZD11
Description		sigma non-opioid intracellular receptor 1	PDZ domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse
	Molecular Function	G Protein-coupled Opioid Receptor Activity Protein Binding	Protein Binding
	Biological Process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide G Protein-coupled Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization	Neurotransmitter Secretion Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Protein Localization To Basolateral Plasma Membrane
Pathways		Potential therapeutics for SARS	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs		Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS
Interacting Genes		14 interacting genes: ANK2 DCAF12 DNAJB5 GHSR GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 VCP	17 interacting genes: ATP2B2 ATP7A CD79B EDEM1 GDPD2 KIF4A MAGI2 MYO1F NLGN3 PLEKHA5 RAB11FIP2 SIGMAR1 SMG8 SNX12 TAF1 TEX11 ZMYM3
Entrez ID		10280	51248
HPRD ID		03580	06622
Ensembl ID		ENSG00000147955	ENSG00000120509
Uniprot IDs		A2A3U5 B4DR71 Q99720	Q5EBL8
PDB IDs		5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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