SIGMAR1 and DNAJB5

		SIGMAR1	DNAJB5
Description		sigma non-opioid intracellular receptor 1	DnaJ heat shock protein family (Hsp40) member B5
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane	Cytosol
	Molecular Function	G Protein-coupled Opioid Receptor Activity Protein Binding	Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide G Protein-coupled Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization	Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding
Pathways		Potential therapeutics for SARS
Drugs		Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS			Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		14 interacting genes: ANK2 DCAF12 DNAJB5 GHSR GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 VCP	12 interacting genes: ANK2 CACNA1A MRFAP1 MYBPC1 NOCT OBSCN SIGMAR1 SMAD2 SMAD3 TAF1 TBPL2 TTN
Entrez ID		10280	25822
HPRD ID		03580	07106
Ensembl ID		ENSG00000147955	ENSG00000137094
Uniprot IDs		A2A3U5 B4DR71 Q99720	O75953
PDB IDs		5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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