POM121 and HOMER3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		POM121	HOMER3
Description		POM121 transmembrane nucleoporin	homer scaffold protein 3
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GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane Nuclear Membrane Host Cell	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Neuron Projection
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding
	Biological Process	Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738)
Interacting Genes		21 interacting genes: AGR2 AP2B1 APC ATXN1 BRCA1 CEP55 CEP76 CERT1 CLDN3 FXR2 GFAP GOLGA2 GYG1 HOMER3 LPXN NFKBIA PAXIP1 RBPMS TEX11 TRIM23 TRIP6	31 interacting genes: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EFHC1 EIF3D FAT1 FRYL GDF15 GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PRCC PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1
Entrez ID		9883	9454
HPRD ID		11448	07270
Ensembl ID		ENSG00000196313	ENSG00000051128
Uniprot IDs		Q96HA1	Q9NSC5
PDB IDs		5T6W	2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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