HOMER3 and FAT1

Number of citations of the paper that reports this interaction (PubMedID 16979624)
11

Data Source:
HPRD (in vitro)

		HOMER3	FAT1
Description		homer scaffold protein 3	FAT atypical cadherin 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Neuron Projection	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry	Epithelial Cell Morphogenesis Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Camera-type Eye Morphogenesis Cell-cell Adhesion
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		31 interacting genes: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EFHC1 EIF3D FAT1 FRYL GDF15 GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PRCC PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1	12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP
Entrez ID		9454	2195
HPRD ID		07270	02986
Ensembl ID		ENSG00000051128	ENSG00000083857
Uniprot IDs		Q9NSC5	Q14517
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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