POM121 and GFAP

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POM121	GFAP
Description		POM121 transmembrane nucleoporin	glial fibrillary acidic protein
Image
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane Nuclear Membrane Host Cell	Cytoplasm Lysosome Cytosol Intermediate Filament Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Regulation Of Protein Complex Assembly Intermediate Filament Organization Regulation Of Chaperone-mediated Autophagy
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation	Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases			Alexander disease
GWAS		Subcutaneous adipose tissue ( 22589738)	Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)
Interacting Genes		21 interacting genes: AGR2 AP2B1 APC ATXN1 BRCA1 CEP55 CEP76 CERT1 CLDN3 FXR2 GFAP GOLGA2 GYG1 HOMER3 LPXN NFKBIA PAXIP1 RBPMS TEX11 TRIM23 TRIP6	51 interacting genes: AKT1 APP AURKB BIRC2 CAMK2A CDK1 CEP76 CFAP206 CRYAB FAM50B GOLGA2 GRAP2 HGS IKBKG KIAA0408 KRT13 KRT15 KRT19 LGALS14 LMO2 MEN1 MOS MYO15B NEFL NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCB1 SRC STAT1 TLE5 TRIM27 TUBGCP4 UBE3A VIM ZC2HC1C
Entrez ID		9883	2670
HPRD ID		11448	00675
Ensembl ID		ENSG00000196313	ENSG00000131095
Uniprot IDs		Q96HA1	A7REI1 P14136
PDB IDs		5T6W	6A9P
Enriched GO Terms of Interacting Partners?
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