HOMER3 and PPP1R18

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HOMER3	PPP1R18
Description		homer scaffold protein 3	protein phosphatase 1 regulatory subunit 18
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Neuron Projection	Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lung cancer ( 28604730)
Interacting Genes		31 interacting genes: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EFHC1 EIF3D FAT1 FRYL GDF15 GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PRCC PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1	37 interacting genes: CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 DES FAM9B FSD2 GOLGA2 HOMER3 KASH5 KCTD9 KRT13 KRT15 KRT19 KRT31 KRT40 LZTS2 MID2 MTUS2 NEFL PDE4DIP PPP1CA PPP1CC SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM69 TSGA10 VPS52
Entrez ID		9454	170954
HPRD ID		07270	11172
Ensembl ID		ENSG00000051128	ENSG00000146112
Uniprot IDs		Q9NSC5	A0A024RCJ8 Q6NYC8
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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