HOMER3 and EFHC1

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		HOMER3	EFHC1
Description		homer scaffold protein 3	EF-hand domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Neuron Projection	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding
	Biological Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases			Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS			Atopic march ( 26542096) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		31 interacting genes: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EFHC1 EIF3D FAT1 FRYL GDF15 GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PRCC PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1	18 interacting genes: CACNA1E DOK7 EFHC2 EIF4ENIF1 GOLGA2 HOMER3 IHO1 IKZF3 KCTD4 KRT15 REL RIMBP3 SH3GLB2 TCF4 TEX11 TRAF2 TRIP6 ZBED1
Entrez ID		9454	114327
HPRD ID		07270	10583
Ensembl ID		ENSG00000051128	ENSG00000096093
Uniprot IDs		Q9NSC5	B2CKC5 Q5JVL4
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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