ENTPD2 and HMBOX1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ENTPD2	HMBOX1
Description		ectonucleoside triphosphate diphosphohydrolase 2	homeobox containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Basement Membrane Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body
	Molecular Function	ATP Binding Nucleoside-diphosphatase Activity Nucleoside-triphosphatase Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Purine Ribonucleoside Diphosphate Catabolic Process Platelet Activation Nucleobase-containing Small Molecule Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity
Pathways		Phosphate bond hydrolysis by NTPDase proteins
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: HMBOX1 STX7	49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		954	79618
HPRD ID		03600	07964
Ensembl ID		ENSG00000054179	ENSG00000147421
Uniprot IDs		Q9Y5L3	D3DSU2 Q6NT76
PDB IDs			2CUF 4J19
Enriched GO Terms of Interacting Partners?
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