AIMP1 and AIMP2

Number of citations of the paper that reports this interaction (PubMedID 9878398)
55

Data Source:
HPRD (in vitro)

		AIMP1	AIMP2
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 1	aminoacyl tRNA synthetase complex interacting multifunctional protein 2
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GO Annotations	Cellular Component	Extracellular Space Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Cell Surface Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	TRNA Binding Cytokine Activity Protein Binding Protein Homodimerization Activity GTPase Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation TRNA Aminoacylation For Protein Translation Apoptotic Process Chemotaxis Inflammatory Response Signal Transduction Cell-cell Signaling Response To Wounding Leukocyte Migration Defense Response To Virus Positive Regulation Of Glucagon Secretion	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases		Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS			Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		8 interacting genes: AIMP2 APP ATP5F1A IQGAP1 MAPK14 MAPK8 RARS1 TSNAX	48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT
Entrez ID		9255	7965
HPRD ID		04676	02915
Ensembl ID		ENSG00000164022	ENSG00000106305
Uniprot IDs		B4DNK3 Q12904	A0A024QZY1 A8MU58 Q13155
PDB IDs		1E7Z 1EUJ 1FL0 4R3Z	4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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