NUMBL and TRAF5

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 75
  • Data Source:
  • BioGRID (two hybrid)

NUMBL

TRAF5

Description NUMB like endocytic adaptor protein TNF receptor associated factor 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941)
  • Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941)
  • Kawasaki disease ( 22446962)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
Interacting Genes 23 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 YWHAG 45 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 COG7 COMMD3 DGKH ENOX2 GOLGA2 GORASP2 HSD17B10 LTBR MAP3K14 MAP3K5 MDM2 NMI NUMBL RAD23A RIPK1 RIPK2 RNF111 SDCBP SEC13 SERPINB9 TBK1 TDP2 THAP1 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 ZFAND6
Entrez ID 9253 7188
HPRD ID 04931 03834
Ensembl ID ENSG00000105245 ENSG00000082512
Uniprot IDs A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0 O00463
PDB IDs 3F0W
Enriched GO Terms of Interacting Partners?
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