TRAF5 and ZFAND6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRAF5	ZFAND6
Description		TNF receptor associated factor 5	zinc finger AN1-type containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Receptor Complex	Cellular_component Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding	Molecular_function DNA Binding Protein Binding Zinc Ion Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Apoptotic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination	Protein Targeting To Peroxisome Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Tumor Necrosis Factor
Pathways			Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		Household income (MTAG) ( 31844048)	Eosinophil counts ( 29403010) Monocyte count ( 29403010) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Type 2 diabetes ( 20581827) White blood cell count ( 29403010)
Interacting Genes		45 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 COG7 COMMD3 DGKH ENOX2 GOLGA2 GORASP2 HSD17B10 LTBR MAP3K14 MAP3K5 MDM2 NMI NUMBL RAD23A RIPK1 RIPK2 RNF111 SDCBP SEC13 SERPINB9 TBK1 TDP2 THAP1 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 ZFAND6	6 interacting genes: CDC34 DNM2 PKN1 TRAF2 TRAF5 UBC
Entrez ID		7188	54469
HPRD ID		03834	18314
Ensembl ID		ENSG00000082512	ENSG00000086666
Uniprot IDs		O00463	Q6FIF0
PDB IDs
Enriched GO Terms of Interacting Partners?
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