TRAF5 and ENOX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRAF5	ENOX2
Description		TNF receptor associated factor 5	ecto-NOX disulfide-thiol exchanger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Receptor Complex	Extracellular Space Cytosol Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding	Nucleic Acid Binding Protein Disulfide Oxidoreductase Activity
	Biological Process	Apoptotic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination	Ultradian Rhythm Regulation Of Growth Oxidation-reduction Process
Pathways
Drugs			Idronoxil
Diseases
GWAS		Household income (MTAG) ( 31844048)
Interacting Genes		45 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 COG7 COMMD3 DGKH ENOX2 GOLGA2 GORASP2 HSD17B10 LTBR MAP3K14 MAP3K5 MDM2 NMI NUMBL RAD23A RIPK1 RIPK2 RNF111 SDCBP SEC13 SERPINB9 TBK1 TDP2 THAP1 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 ZFAND6	9 interacting genes: CIB3 ENOX1 INTS4 MAGEA11 MLLT6 SNRPA SRPK2 TRAF5 TUBB4B
Entrez ID		7188	10495
HPRD ID		03834	02234
Ensembl ID		ENSG00000082512	ENSG00000165675
Uniprot IDs		O00463	Q16206 Q32ND0
PDB IDs
Enriched GO Terms of Interacting Partners?
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