NUMBL and EPS15

  • Number of citations of the paper that reports this interaction (PubMedID 9303539)
  • 115
  • Data Source:
  • HPRD (in vitro, in vivo)

NUMBL

EPS15

Description NUMB like endocytic adaptor protein epidermal growth factor receptor pathway substrate 15
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941)
  • Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941)
  • Kawasaki disease ( 22446962)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
Interacting Genes 23 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 YWHAG 51 interacting genes: AGFG1 AGFG2 AP1G1 AP2A1 AP2A2 CLINT1 CORO7 CRK DNM1 DNM2 EGFR ELF3 EPN1 EPN2 FCHO1 FCHO2 GRB2 HGS ITSN1 LAPTM5 MAPK14 MOB4 MTNR1A NAGPA NEDD4 NUMB NUMBL OPTN PPT1 PRKN REPS2 RNF11 SCAMP1 SGIP1 SNAP91 SPART SPOPL STAM2 STAMBP STON2 SYNJ1 TFAP2A UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBQLN1 USP8
Entrez ID 9253 2060
HPRD ID 04931 08968
Ensembl ID ENSG00000105245 ENSG00000085832
Uniprot IDs A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0 B7Z240 P42566
PDB IDs 3F0W 1C07 1EH2 1F8H 1FF1 2IV9 2JXC 4RH5 4RH9 4RHG 4S0G 5AWT 5AWU 5JP2
Enriched GO Terms of Interacting Partners?
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