EPS15 and NUMBL

  • Number of citations of the paper that reports this interaction (PubMedID 9303539)
  • 115
  • Data Source:
  • HPRD (in vitro, in vivo)

EPS15

NUMBL

Description epidermal growth factor receptor pathway substrate 15 NUMB like endocytic adaptor protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941)
  • Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941)
  • Kawasaki disease ( 22446962)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
Interacting Genes 51 interacting genes: AGFG1 AGFG2 AP1G1 AP2A1 AP2A2 CLINT1 CORO7 CRK DNM1 DNM2 EGFR ELF3 EPN1 EPN2 FCHO1 FCHO2 GRB2 HGS ITSN1 LAPTM5 MAPK14 MOB4 MTNR1A NAGPA NEDD4 NUMB NUMBL OPTN PPT1 PRKN REPS2 RNF11 SCAMP1 SGIP1 SNAP91 SPART SPOPL STAM2 STAMBP STON2 SYNJ1 TFAP2A UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBQLN1 USP8 23 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 YWHAG
Entrez ID 2060 9253
HPRD ID 08968 04931
Ensembl ID ENSG00000085832 ENSG00000105245
Uniprot IDs B7Z240 P42566 A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0
PDB IDs 1C07 1EH2 1F8H 1FF1 2IV9 2JXC 4RH5 4RH9 4RHG 4S0G 5AWT 5AWU 5JP2 3F0W
Enriched GO Terms of Interacting Partners?
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