EPS15 and SNAP91

Number of citations of the paper that reports this interaction (PubMedID 12807910)
25

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		EPS15	SNAP91
Description		epidermal growth factor receptor pathway substrate 15	synaptosome associated protein 91
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Clathrin-coated Pit Basal Plasma Membrane Membrane Aggresome Apical Plasma Membrane AP-2 Adaptor Complex Early Endosome Membrane Intracellular Membrane-bounded Organelle Ciliary Membrane Postsynapse Glutamatergic Synapse	Plasma Membrane Clathrin-coated Pit Synaptic Vesicle Clathrin-coated Vesicle Presynaptic Membrane Extrinsic Component Of Presynaptic Endocytic Zone Membrane
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Cadherin Binding	SNARE Binding Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein Kinase Binding Clathrin Heavy Chain Binding
	Biological Process	Positive Regulation Of Receptor Recycling Golgi To Endosome Transport Vesicle Organization Receptor-mediated Endocytosis Of Virus By Host Cell Endocytic Recycling Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Proliferation Viral Entry Into Host Cell Clathrin Coat Assembly Membrane Organization Postsynaptic Neurotransmitter Receptor Internalization	Endocytosis Vesicle Budding From Membrane Protein Transport Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Clathrin Coat Assembly Synaptic Vesicle Endocytosis Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis
Pathways		EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) IgE grass sensitization ( 22036096) PR interval ( 30046033)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Electrodermal activity ( 25387706) Macular thickness ( 30535121) Schizophrenia ( 28991256 29483656 30285260)
Interacting Genes		51 interacting genes: AGFG1 AGFG2 AP1G1 AP2A1 AP2A2 CLINT1 CORO7 CRK DNM1 DNM2 EGFR ELF3 EPN1 EPN2 FCHO1 FCHO2 GRB2 HGS ITSN1 LAPTM5 MAPK14 MOB4 MTNR1A NAGPA NEDD4 NUMB NUMBL OPTN PPT1 PRKN REPS2 RNF11 SCAMP1 SGIP1 SNAP91 SPART SPOPL STAM2 STAMBP STON2 SYNJ1 TFAP2A UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBQLN1 USP8	9 interacting genes: AP2A2 AP2B1 DNAJC5 EPS15 NECAP1 OGT PLCG1 TRAF3IP1 TUBA1B
Entrez ID		2060	9892
HPRD ID		08968	06391
Ensembl ID		ENSG00000085832	ENSG00000065609
Uniprot IDs		B7Z240 P42566	B7Z2N2 E9PDG8 H0UI15 O60641
PDB IDs		1C07 1EH2 1F8H 1FF1 2IV9 2JXC 4RH5 4RH9 4RHG 4S0G 5AWT 5AWU 5JP2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?