NAV2 and PIAS2

  • Number of citations of the paper that reports this interaction (PubMedID 16189514)
  • 1016
  • Data Source:
  • BioGRID (two hybrid, two hybrid)
  • HPRD (two hybrid)

NAV2

PIAS2

Description neuron navigator 2 protein inhibitor of activated STAT 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to drug ( 30420678)
  • Atrial fibrillation ( 30061737 29892015)
  • Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117)
  • Coronary artery aneurysm in Kawasaki disease ( 27171184)
  • General cognitive ability ( 29844566)
  • Hepatitis ( 25705159)
  • Low susceptibility to hepatitis C infection ( 31206233)
  • Macular thickness ( 30535121)
  • Monobrow ( 27182965)
  • Obesity-related traits ( 23251661)
  • PR interval ( 30046033)
  • Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
  • Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
  • Waist circumference ( 28552196)
Interacting Genes 12 interacting genes: ADAT2 APC CFAP58 ING4 ING5 MORF4L1 PIAS2 PRPF3 PSTPIP1 RBM15 RBM15B RRAS 72 interacting genes: ACY3 ADA AKT1 AR C1QA CCHCR1 CCNDBP1 CDCA8 CHMP4B CLDN2 CREBBP CTBP1 DDX39B DNMT3A ELK1 ESR1 ESR2 FLI1 GFAP GLUL GOLGA2 GRM8 GTF2I GTF2IRD1 HDAC3 HUWE1 JUN LMNA LMNB1 MAPK8 MAPKAPK2 MBD1 MITF MSX2 MX2 NAV2 NR3C1 PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 RUFY1 SIAH1 SIAH2 SMAD3 SMAD4 SNAI2 SNIP1 SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 TICAM2 TP53 TRIM23 TRIM27 TRIM55 TRIM63 TSR2 UBE2I UBE2L3 ZBED1 ZBTB8A ZNF451
Entrez ID 89797 9063
HPRD ID 07385 06944
Ensembl ID ENSG00000166833 ENSG00000078043
Uniprot IDs A7E2D6 Q8IVL1 A0A024RC49 O75928 Q2TA77
PDB IDs 2YRN 2ASQ 4FO9
Enriched GO Terms of Interacting Partners?
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