PIAS2 and ZBED1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PIAS2	ZBED1
Description		protein inhibitor of activated STAT 2	zinc finger BED-type containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm PML Body Nuclear Speck	Nuclear Chromatin Nucleoplasm Centrosome Nuclear Membrane
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Zinc Ion Binding SUMO Transferase Activity Ubiquitin Protein Ligase Binding Androgen Receptor Binding SUMO Ligase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Sumoylation Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Androgen Receptor Signaling Pathway	Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	SUMOylation of chromatin organization proteins
Drugs
Diseases
GWAS
Interacting Genes		72 interacting genes: ACY3 ADA AKT1 AR C1QA CCHCR1 CCNDBP1 CDCA8 CHMP4B CLDN2 CREBBP CTBP1 DDX39B DNMT3A ELK1 ESR1 ESR2 FLI1 GFAP GLUL GOLGA2 GRM8 GTF2I GTF2IRD1 HDAC3 HUWE1 JUN LMNA LMNB1 MAPK8 MAPKAPK2 MBD1 MITF MSX2 MX2 NAV2 NR3C1 PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 RUFY1 SIAH1 SIAH2 SMAD3 SMAD4 SNAI2 SNIP1 SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 TICAM2 TP53 TRIM23 TRIM27 TRIM55 TRIM63 TSR2 UBE2I UBE2L3 ZBED1 ZBTB8A ZNF451	29 interacting genes: AMOTL2 ATRX C1orf109 DGCR6 EFHC1 FABP4 FANCG GPN1 GPSM1 KDM1A KLHL40 LRRC20 MLH1 NIF3L1 NIP7 NUDT18 PIAS2 PRKAA1 PRKAR1A PSAP RENBP SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2B TTR UBE2I UCHL5
Entrez ID		9063	9189
HPRD ID		06944	02170
Ensembl ID		ENSG00000078043	ENSG00000214717
Uniprot IDs		A0A024RC49 O75928 Q2TA77	A0A024RBU4 O96006
PDB IDs		2ASQ 4FO9	2CT5
Enriched GO Terms of Interacting Partners?
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