PIAS2 and ZBTB8A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PIAS2	ZBTB8A
Description		protein inhibitor of activated STAT 2	zinc finger and BTB domain containing 8A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm PML Body Nuclear Speck	Cellular_component Nucleus
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Zinc Ion Binding SUMO Transferase Activity Ubiquitin Protein Ligase Binding Androgen Receptor Binding SUMO Ligase Activity	Molecular_function DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Sumoylation Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Androgen Receptor Signaling Pathway	Biological_process
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS
Interacting Genes		72 interacting genes: ACY3 ADA AKT1 AR C1QA CCHCR1 CCNDBP1 CDCA8 CHMP4B CLDN2 CREBBP CTBP1 DDX39B DNMT3A ELK1 ESR1 ESR2 FLI1 GFAP GLUL GOLGA2 GRM8 GTF2I GTF2IRD1 HDAC3 HUWE1 JUN LMNA LMNB1 MAPK8 MAPKAPK2 MBD1 MITF MSX2 MX2 NAV2 NR3C1 PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 RUFY1 SIAH1 SIAH2 SMAD3 SMAD4 SNAI2 SNIP1 SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 TICAM2 TP53 TRIM23 TRIM27 TRIM55 TRIM63 TSR2 UBE2I UBE2L3 ZBED1 ZBTB8A ZNF451	52 interacting genes: AEN AP1M1 AP2M1 ARMCX1 BAZ2B BYSL CCDC33 CDKL3 CEP70 DDX6 DVL2 EIF1AD EP300 FAM161A FXR2 GPATCH2L KAT5 KAT7 KIF5B KIF9 KIFC3 LMO3 LNX1 MCM10 MFAP1 MYO15B NTAQ1 PAXIP1 PIAS2 PRKAA2 PRPF3 PSMC1 RAD23A RPL9 SDCBP SYT6 TNIP3 TRIM41 UBE2I YES1 ZBTB24 ZBTB48 ZBTB49 ZCCHC10 ZGPAT ZMAT2 ZNF138 ZNF250 ZNF276 ZNF408 ZNF417 ZNF587
Entrez ID		9063	653121
HPRD ID		06944	18902
Ensembl ID		ENSG00000078043	ENSG00000160062
Uniprot IDs		A0A024RC49 O75928 Q2TA77	D3DPQ1 Q96BR9
PDB IDs		2ASQ 4FO9
Enriched GO Terms of Interacting Partners?
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