PIAS2 and PLAG1

Number of citations of the paper that reports this interaction (PubMedID 15208321)
11

Data Source:
BioGRID (pull down)

		PIAS2	PLAG1
Description		protein inhibitor of activated STAT 2	PLAG1 zinc finger
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm PML Body Nuclear Speck	Nucleus Nucleoplasm Centrosome Cytosol Nuclear Speck
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Zinc Ion Binding SUMO Transferase Activity Ubiquitin Protein Ligase Binding Androgen Receptor Binding SUMO Ligase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Sumoylation Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Androgen Receptor Signaling Pathway	Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Gland Morphogenesis Multicellular Organism Growth Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glial Cell Proliferation Prostate Gland Growth
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS			Birth weight ( 31043758) Heel bone mineral density ( 30598549) Height ( 28552196 25282103 25429064 19396169 19343178 19893584 31562340 18391951 20189936) Hip circumference adjusted for BMI ( 25673412)
Interacting Genes		72 interacting genes: ACY3 ADA AKT1 AR C1QA CCHCR1 CCNDBP1 CDCA8 CHMP4B CLDN2 CREBBP CTBP1 DDX39B DNMT3A ELK1 ESR1 ESR2 FLI1 GFAP GLUL GOLGA2 GRM8 GTF2I GTF2IRD1 HDAC3 HUWE1 JUN LMNA LMNB1 MAPK8 MAPKAPK2 MBD1 MITF MSX2 MX2 NAV2 NR3C1 PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 RUFY1 SIAH1 SIAH2 SMAD3 SMAD4 SNAI2 SNIP1 SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 TICAM2 TP53 TRIM23 TRIM27 TRIM55 TRIM63 TSR2 UBE2I UBE2L3 ZBED1 ZBTB8A ZNF451	5 interacting genes: KPNA2 PIAS1 PIAS2 PIAS4 SMAD3
Entrez ID		9063	5324
HPRD ID		06944	04321
Ensembl ID		ENSG00000078043	ENSG00000181690
Uniprot IDs		A0A024RC49 O75928 Q2TA77	A0A024R7Z0 Q6DJT9
PDB IDs		2ASQ 4FO9
Enriched GO Terms of Interacting Partners?
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