NAV2 and RRAS

Number of citations of the paper that reports this interaction (PubMedID 15031288)
32

Data Source:
HPRD (in vitro)

		NAV2	RRAS
Description		neuron navigator 2	RAS related
Image
GO Annotations	Cellular Component	Interstitial Matrix Nucleoplasm	Plasma Membrane Focal Adhesion Extracellular Exosome
	Molecular Function	DNA Helicase Activity Protein Binding ATP Binding Heparin Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein-containing Complex Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Nervous System Development Sensory Perception Of Sound Sensory Perception Of Smell Locomotory Behavior Optic Nerve Development Glossopharyngeal Nerve Development Vagus Nerve Development Neurogenesis DNA Duplex Unwinding	Leukocyte Differentiation Ras Protein Signal Transduction Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Cell Migration Positive Regulation Of Angiogenesis Regulation Of Protein Kinase B Signaling Face Morphogenesis Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Vasculogenesis
Pathways			SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Atrial fibrillation ( 30061737 29892015) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) Coronary artery aneurysm in Kawasaki disease ( 27171184) General cognitive ability ( 29844566) Hepatitis ( 25705159) Low susceptibility to hepatitis C infection ( 31206233) Macular thickness ( 30535121) Monobrow ( 27182965) Obesity-related traits ( 23251661) PR interval ( 30046033) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Smoking initiation (ever regular vs never regular) ( 30679032) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306) Waist circumference ( 28552196)	Estimated glomerular filtration rate ( 31152163) Pulse pressure ( 27618447) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27618447)
Interacting Genes		12 interacting genes: ADAT2 APC CFAP58 ING4 ING5 MORF4L1 PIAS2 PRPF3 PSTPIP1 RBM15 RBM15B RRAS	15 interacting genes: ACY3 AFDN ARAF BCL2 EEF1A1 EPHB2 MRPL36 NAV2 NCK1 PPP2CA RAF1 RALGDS RASIP1 RASSF5 SOS1
Entrez ID		89797	6237
HPRD ID		07385	01299
Ensembl ID		ENSG00000166833	ENSG00000126458
Uniprot IDs		A7E2D6 Q8IVL1	A0A024QZF2 P10301
PDB IDs		2YRN	2FN4
Enriched GO Terms of Interacting Partners?
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