KRT38 and LHX4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		KRT38	LHX4
Description		keratin 38	LIM homeobox 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Nuclear Chromatin Nucleus
	Molecular Function	Structural Molecule Activity Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Keratinization Cornification	Placenta Development Motor Neuron Axon Guidance Animal Organ Morphogenesis Medial Motor Column Neuron Differentiation Neuron Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Keratinization Formation of the cornified envelope	Regulation of expression of SLITs and ROBOs
Drugs
Diseases			Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Interacting Genes		46 interacting genes: AMOTL2 ANKRD36BP1 BEX2 C19orf57 C1orf216 CCDC146 CD300A CEP57L1 FAM90A1 GLRX3 GNG10 HAUS1 HDAC4 HGS HMG20B HOXA1 KDM1A KLHL38 KRT2 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT79 KRT8 KRT81 KRT83 LHX4 MAGEB4 PIK3R2 PIN1 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 TXLNA TXLNB TXNDC5 USHBP1 ZFYVE21 ZNF20 ZNF417 ZNF587	22 interacting genes: ADAMTSL4 AXIN1 CHCHD2 FDX2 GOLGA2 IFT172 IKZF1 KRT38 KRT40 LDB2 LONRF1 NRF1 ORC6 SH2D1A SNRNP25 SSX1 TCAP TCF4 TP53BP2 TXNDC5 UBQLN1 USP2
Entrez ID		8687	89884
HPRD ID		05176	03686
Ensembl ID		ENSG00000171360	ENSG00000121454
Uniprot IDs		O76015	A0A0S2Z5S4 Q969G2
PDB IDs			5HOD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?