LHX4 and SSX1

Number of citations of the paper that reports this interaction (PubMedID 17667940)
13

Data Source:
BioGRID (two hybrid)

		LHX4	SSX1
Description		LIM homeobox 4	SSX family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding	Nucleic Acid Binding Transcription Corepressor Activity Protein Binding
	Biological Process	Placenta Development Motor Neuron Axon Guidance Animal Organ Morphogenesis Medial Motor Column Neuron Differentiation Neuron Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Regulation of expression of SLITs and ROBOs
Drugs
Diseases		Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)	Synovial sarcoma
GWAS
Interacting Genes		22 interacting genes: ADAMTSL4 AXIN1 CHCHD2 FDX2 GOLGA2 IFT172 IKZF1 KRT38 KRT40 LDB2 LONRF1 NRF1 ORC6 SH2D1A SNRNP25 SSX1 TCAP TCF4 TP53BP2 TXNDC5 UBQLN1 USP2	3 interacting genes: FUBP3 LHX4 MAGEC2
Entrez ID		89884	6756
HPRD ID		03686	02428
Ensembl ID		ENSG00000121454	ENSG00000126752
Uniprot IDs		A0A0S2Z5S4 Q969G2	Q16384
PDB IDs		5HOD
Enriched GO Terms of Interacting Partners?
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