ZNF587 and HMBOX1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF587	HMBOX1
Description		zinc finger protein 587	homeobox containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)	Obesity-related traits ( 23251661)
Interacting Genes		43 interacting genes: ADAMTSL4 CARD9 CCDC136 CEP44 CEP70 CSRNP1 FSD2 GOLGA2 GOPC HMBOX1 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP5-9 MDFI MEOX2 MID2 MTUS2 NOTCH2NLA PLSCR1 PNMA2 PRPF31 RUNDC3A SMAD9 SPRY2 SSX2IP STX11 TCF4 TMCC2 TNS2 TRAF1 TRIM36 TRIM41 TRIM54 TSGA10 ZBTB8A ZNF417	49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		84914	79618
HPRD ID		15864	07964
Ensembl ID		ENSG00000198466	ENSG00000147421
Uniprot IDs		Q96SQ5	D3DSU2 Q6NT76
PDB IDs			2CUF 4J19
Enriched GO Terms of Interacting Partners?
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