L3MBTL3 and LZTR1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		L3MBTL3	LZTR1
Description		L3MBTL histone methyl-lysine binding protein 3	leucine zipper like transcription regulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane
	Molecular Function	Molecular_function DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding	DNA-binding Transcription Factor Activity Ras GTPase Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Macrophage Differentiation Granulocyte Differentiation Erythrocyte Maturation	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Body mass index ( 25673413) Breast cancer ( 29059683 29058716) Breast cancer (estrogen-receptor negative) ( 29058716) C-reactive protein levels ( 30388399) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 20881960 25282103 25429064 23563607 31562340 18391951) Hematocrit ( 27863252) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 25673412) Influenza A (H1N1) infection ( 26379185) Lymphocyte counts ( 27863252) Mild influenza (H1N1) infection ( 26379185) Multiple sclerosis ( 31604244 27386562) Offspring birth weight ( 31043758) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight ( 28552196)
Interacting Genes		30 interacting genes: ASB6 BANP BYSL DNMT1 KDM1A LRRK2 LSM4 LZTR1 MAPK3 MAPK9 MORF4L1 MORF4L2 NGB OAZ3 PDE6G PHC2 PIK3R3 PLEKHF1 PLEKHF2 POLR2L PRKAA1 PRKAA2 SNRPB SOX2 SP100 SUMO1P1 THRA TSTD2 TTC19 ZCWPW1	54 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MRAS MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3
Entrez ID		84456	8216
HPRD ID		11222	08992
Ensembl ID		ENSG00000198945	ENSG00000099949
Uniprot IDs		Q96JM7	A0A384NL67 Q8N653
PDB IDs		1WJQ 1WJS 3UT1 4FL6 4L59
Enriched GO Terms of Interacting Partners?
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