L3MBTL3 and PLEKHF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		L3MBTL3	PLEKHF1
Description		L3MBTL histone methyl-lysine binding protein 3	pleckstrin homology and FYVE domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Nucleus Lysosome Lysosomal Membrane Endosome Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Macrophage Differentiation Granulocyte Differentiation Erythrocyte Maturation	Apoptotic Process Endosome Organization Positive Regulation Of Autophagy Vesicle Organization Protein Localization To Plasma Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Body mass index ( 25673413) Breast cancer ( 29059683 29058716) Breast cancer (estrogen-receptor negative) ( 29058716) C-reactive protein levels ( 30388399) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 20881960 25282103 25429064 23563607 31562340 18391951) Hematocrit ( 27863252) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 25673412) Influenza A (H1N1) infection ( 26379185) Lymphocyte counts ( 27863252) Mild influenza (H1N1) infection ( 26379185) Multiple sclerosis ( 31604244 27386562) Offspring birth weight ( 31043758) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight ( 28552196)	Body mass index ( 26426971)
Interacting Genes		30 interacting genes: ASB6 BANP BYSL DNMT1 KDM1A LRRK2 LSM4 LZTR1 MAPK3 MAPK9 MORF4L1 MORF4L2 NGB OAZ3 PDE6G PHC2 PIK3R3 PLEKHF1 PLEKHF2 POLR2L PRKAA1 PRKAA2 SNRPB SOX2 SP100 SUMO1P1 THRA TSTD2 TTC19 ZCWPW1	3 interacting genes: KIFBP L3MBTL3 TNNT1
Entrez ID		84456	79156
HPRD ID		11222	15146
Ensembl ID		ENSG00000198945	ENSG00000166289
Uniprot IDs		Q96JM7	B4DWN9 Q96S99
PDB IDs		1WJQ 1WJS 3UT1 4FL6 4L59
Enriched GO Terms of Interacting Partners?
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